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Gene expression (4,000+ genes) A 2018 review of Broad Institute Connectivity Map data reported that GHK modulates the expression of more than 4,000 human genes, spanning collagen synthesis, DNA repair, antioxidant defense, and anti-inflammatory pathways (Pickart & Margolina, International Journal of Molecular Sciences, 2018)

Bifidobacterium and Lactobacillus plantarum not only increased tear secretion but also repaired CECs and reduced inflammatory markers like TNF- and IL-1 (Yun et al., 2021)

Mice that lack HSL show only a minor defect in lipolysis, are cold tolerant, and demonstrate a dramatic accumulation of DAGs in adipose tissue (39-41)

Approximately 11.9-fold increase in endogenous MOTS-c levels have been found in skeletal muscle following exercise (compared to pre-exercise values), and this increase can remain for 4 hours following exercise (19)

M., Ricardo-da-Silva, J